Hoek et al developed an equation for estimating glomerular filtration rate (GFR) for adults using cystatin C. The authors are from the University of Amsterdam.



(1) cystatin C in mg/L determined by a particle-enhanced immunonephelometric method (Dade-Behring) with a normal reference range of 0.5 to 0.96 mg/L.


estimated GFR in mL per min per 1.73 square m BSA =

= (80.35 / (cystatin C)) - 4.32



• The reference GFR was determined by 125I-iothalamate.


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