Yan et al used a number of clinical findings to distinguish a Zika infection from Dengue Fever. The authors are from the National University Health System and Tan Tock Seng Hospital in Singapore.
Findings associated with Zika virus infection:
(1) conjunctivitis
(2) normal platelet count
(3) normal monocyte count
The AUC under the ROC curve was 0.95 for the model with all 3 of these parameters.
A rash may be a common finding in Zika in some outbreaks.
Findings associated with dengue:
(1) myalgia
(2) headache
In more serious dengue cases thrombocytopenia, elevated AST and ALT, and monocytosis are seen.
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