Goshima et al reported a number of findings seen on computed tomography (CT) scans that can help to distinguish xanthogranulomatous cholecystitis from gallbladder cancer. The authors are from the University of Pittsburgh.


Findings on CT scan associated with xanthogranulomatous cholecystitis:

(1) diffuse thickening of the gallbladder wall

(2) mucosal line continuous

(3) intramural hypo-attenuated nodules

(4) absence of macroscopic invasion into the liver

(5) absence of dilatation of intrahepatic bile ducts


The presence of 3 or more of these findings was associated with xanthogranulomatous cholecystitis.



• The sensitivity was 83% with specificity 100%.

• The diagnostic accuracy was 91%.


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