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Features of a Hereditary Deficiency of Alpha-2 Antiplasmin

Specialty:

Hematology Oncology
Clinical Laboratory
Genetics

Objective:

ICD-10:

Description:

Alpha-2 antiplasmin inhibits plasmin which lysis fibrin. Deficiency of alpha-2 antiplasmin results in increased fibrinolysis, with a tendency to delayed bleeding due to lysis of the hemostatic plug. An hereditary deficiency has a familial distribution.

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