Fatigue may significantly impair the quality of life for a patient with advanced heart failure. It is often multifactoral. Finding the causes allows for interventions that may be able to improve the patient's condition.
Reasons for fatigue in a patient with heart failure:
(1) poor sleep associated with
(1a) orthopnea or paroxysmal nocturnal dyspnea
(1b) depression
(1c) sleep apnea
(1d) drug effects
(2) anemia associated with:
(2a) chronic gastrointestinal blood loss associated with aspirin therapy
(2b) anemia of chronic disease
(2c) comorbid conditions
(3) complications of diuretics with overdiuresis and/or hypokalemia
(4) effects of beta-blockers
(5) depression and/or anxiety
(6) impaired oxygen delivery
(7) deconditioning
(8) obesity and poor nutrition
(9) poor adherence
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