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False Elevation of IgG and IgA Concentrations By Nephelometry Due to IgM Monocloncal Protein

Specialty:

Clinical Laboratory
Nephrology, Urology, Obstetrics & Gynecology, Pedatrics, Genetics
Cardiology
Emergency Medicine & Critical Care
Emergency Medicine & Critical Care

Objective:

ICD-10:

Description:

Some patients with a serum IgM monoclonal protein may show a false elevation of IgG and IgA concentrations as measured by nephelometry. Pretreatment of the serum by a reducing agent (beta-mercaptoethanol) may remove the interference.

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