Patient selection: Crohn's disease
Outcome: relapse, surgery or complicated course
Factors associated with high risk:
(1) younger age at onset (age < 40 years used elsewhere)
(2) smoking
(3) longer duration of the disease
(4) early therapy with corticosteroids
(5) presence of fistulizing perianal Crohn's disease
(6) history of previous intestinal resection (? stricturing disease)
(7) disease located in rectum, jejunum or upper GI tract
(8) extensive disease
(9) anemia (low hemoglobin)
(10) low serum albumin
(11) high serum C-reactive protein
(12) high fecal calprotectin concentration
(13) deep ulcerations seen on endoscopy
If none of these factors are present, then the patient is low risk.
If multiple factors are present, then the patient is high risk.