A patient with a myeloproliferative disorder may have a number of symptoms that can significantly impact his or her quality of life.
Common symptoms:
(1) fatigue
(2) night sweats
(3) pruriits
(4) bone pain
Other symptoms that may occur:
(1) fever
(2) unintended weight loss
(3) dyspnea
(4) pains in the back, legs or arms
(5) splenic pain or discomfort (associated with splenomegaly)
(6) numbness in the legs and/or hands
Worsening of symptoms may be a manifestation of:
(1) disease progression
(2) physical deconditioning
(3) depression or other emotional response
(4) worsening of comorbid conditions
(5) adverse effects of therapy
