Factors affecting the quality of life for a patient with psoriasis:
(1) extent and visibility of the skin lesions
(2) withdrawal from contact or other negative reactions by family, friends and acquaintances
(3) psychological reaction by the patient (embarrassment, anxiety, depression, shame, etc)
(4) need to cover up the lesions, leading to excessive clothing or avoidance of situations where the lesions might be exposed
(5) negative impact on work and income
(6) negative impact on social activities and hobbies
(7) gender, with women tending to have a worse quality of life
(8) effectiveness of therapy (with failures leading to frustration)
(9) negative response to the stress (overeating, alcohol abuse, drug abuse, etc)
(10) complications of the disease (psoriatic arthritis, etc) or its therapy