Li et al evaluated serum preoperative fibrinogen and albumin concentrations and correlated them with the prognosis for patients with skull base chordoma. The authors are from multiple institutions in China.
Patient selection: skull base chordoma
Parameters:
(1) preoperative plasma fibrinogen in g/L
(2) preoperative serum albumin in g/L
Fibrinogen
Albumin
Score
fibrinogen >= 3.29 g/L
< 44.6 g/L
2
fibrinogen >= 3.29 g/L
>= 44.6 g/L
1
fibrinogen < 3.29 g/L
< 44.6 g/L
1
fibrinogen < 3.29
>= 44.6 g/L
0
total score =
= SUM(points for both parameters)
Interpretation:
• minimum score: 0
• maximum score: 2
• The higher the score the worse the prognosis.
FA Score
HR progression-free survival
HR overall survival
0
1
1
1
1.7
1.3
2
1.8
4.0
Performance:
• The area under the ROC curve for 5-year overall survival is 0.64.
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