Scleromyxedema is a systemic disorder with extracutaneous manifestations and a number of complications.
(1) dermatoneuro syndrome
(2) arthralgias or arthritis
(3) neuropathy and/or carpal tunnel syndrome
(4) cardiac disease (mucinous cardiomyopathy, ischemia and/or heart failure)
(7) esophageal dysmotility
(8) bilateral macular edema
(9) Raynaud's phenomenon
(10) Sjogren syndrome
(11) dyspnea on exertion, decreased pulmonary diffusion capacity and/or pulmonary fibrosis
(12) hematologic disorder (myelodysplasia, lymphoma)
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