The GISSI-1 Study determined the extent of myocardial injury after acute myocardial infarction based on the number of ST segments showing elevations. The GISSI (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto) study was performed at multiple university hospitals in Italy.
Lead
Change in ST segment
Points for Elevation
limb lead
< 1 mm
0
>= 1 mm
1
precordial lead, non inferior MI
< 2 mm
0
>= 2 mm
1
precordial lead, inferior MI
ABS(value) < 2 mm
0
ABS(value) >= 2 mm
1
number of leads showing ST segment elevation =
= SUM(number of leads meeting criteria for ST segment elevation)
Interpretation:
• minimum number of leads: 0
• maximum number of leads: 12
• The greater the number of leads the larger the extent of myocardial injury.
Number of Leads
Myocardial Injury
0 or 1
NA
2 or 3
small
4 or 5
modest (moderate)
6 or 7
large
>= 8
extensive
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