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Evaluation of a Mother and Offspring for Evidence of Incest Based on Analysis of Alleles at Highly Heterozygous Loci

Specialty:

Genetics

Objective:

ICD-10:

Description:

Comparison of the alleles shown by both the mother and an offspring at highly heterozygous loci can aid in the evaluation of suspected incest. Wenk et al calculated the likelihood ratios for various phenotypic patterns. If the alleles of the loci are independently inherited, then the product of the likelihood ratios can be calculated to give the total likelihood ratio.

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