European Federation of Neurological Societies and the Peripheral Nerve Society reported criteria for the diagnosis of Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP). One element involves supportive features.

Supportive findings:

(1) elevated CSF protein AND CSF WBC count < 10 per microliter

(2) MRI findings: gadolinium enhancement and/or hypertrophy of one or more of:

(2a) the cause equina, lumbosacral or cervical nerve roots

(2b) brachial plexus

(2c) lumbosacral plexus

(3) abnormal sensory electrophysiology in >= 1 nerve

(3a) normal sural AND (abnormal median or radial sensory nerve action potentials SNAPS at the wrist) with exclusion of carpal tunnel syndrome

(3b) conduction velocity < 80% of lower limit of normal

(3c) conduction velocity < 70% if SNAP amplitude is < 80% of lower limit of normal

(3d) delayed somatosensory evoked potentials without CNS disease

(4) objective clinical improvement after immunomodulatory therapy

(5) nerve biopsy shows definite demyelination and/or remyelination on EM or on teased fiber analysis

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