EULAR developed a disease activity index for primary Sjogren's syndrome called the ESSDAI. This consists of 12 subscores measuring various components of disease activity. The authors are from the European League Against Rheumatism Sjogren's Task Force.
Patient selection: primary Sjogren's syndrome
Exclude: muscle weakness due to corticosteroids
Parameters for muscle subscore:
(1) myositis by EMG or biopsy
(2) weakness
(3) elevated serum creatine kinase (CK) relative to upper limit of normal (ULN)
|
Parameter |
Finding |
Points |
|
myositis |
none |
0 |
|
|
mild active |
1 |
|
|
moderately active |
2 |
|
|
highly active |
3 |
|
weakness |
none |
0 |
|
|
mild |
2 |
|
|
moderate or marked |
3 |
|
serum CK |
normal (<= ULN) |
0 |
|
|
> ULN and <= 2 * ULN |
1 |
|
|
> 2 * ULN and <= 4 * ULN |
2 |
|
|
> 4 times ULN |
3 |
subscore weighting: 6
subscore for muscle symptoms =
= MAX(points for the 3 parameters) * (weighting)
Interpretation:
• minimum subscore: 0
• maximum subscore: 18
|
Subscore |
Disease Activity |
|
0 |
no |
|
6 |
low |
|
12 |
moderate |
|
18 |
high |
Specialty: Immunology/Rheumatology
