EULAR Primary Sjogren’s Syndrome Disease Activity (ESSDAI): Biological Subscore

Description

EULAR developed a disease activity index for primary Sjogren's syndrome called the ESSDAI. This consists of 12 subscores measuring various components of disease activity. The authors are from the European League Against Rheumatism Sjogren's Task Force.

Patient selection: primary Sjogren's syndrome

Parameters for biological subscore:

(1) complement levels

(2) gamma globulin levels

(3) cryoglobulin

Parameters	Findings	Points
complement levels	normal	0
	clonal	1
	decreased (low C3, C4 or CH50)	1
gamma globulin	normal	0
	elevated with IgG level 16 to 20 g/L	1
	elevated with IgG level > 20 g/L	2
	decreased with IgG level < 5 g/L	2
cryoglobulin	absent	0
	present	2

subscore weighting: 1

subscore for constitutional symptoms =

= MAX(points for the parameters) * (weighting)

Interpretation:

• minimum subscore: 0

• maximum subscore: 2

Subscore	Disease Activity
0	no
1	low
2	moderate

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EULAR Primary Sjogren’s Syndrome Disease Activity (ESSDAI): Biological Subscore

Description

Specialty