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Estimating the Percent Prothrombin Complex Activity from the INR

Specialty:

Hematology Oncology
Clinical Laboratory

Objective:

ICD-10:

Description:

A vitamin K antagonist such as coumadin will result in reduced level of coagulation factor activity in the prothrombin complex (prothrombin, Factor 9, Factor 10 and Factor 7). This will result in a prolongation of the prothrombin time (PT), which in turn will be associated with an increase in the INR (International Normalized Ratio).

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