Description

The ratio f describes the relationship between the whole body hematocrit and the venous hematocrit (see 02.10.05). The whole body hematocrit can be used to calculate a patient's whole body red cell mass (RCM). Balga et al evaluated the impact of various values of f on the calculated RCM. The authors are University Hospital in Bern, Switzerland.


 

f =

= (whole body hematocrit) / (venous hematocrit)

 

Subjects for study: males from 7.9 to 88.4 and females from 15.5 to 80.5 years of age

Values of f

Female

Male

low end of range

0.757

0.766

mean

0.918

0.908

high end of range

1.157

1.106

 

The mean value for men and women was 0.911

 

calculated red cell volume in liters =

= (f ratio) * (venous hematocrit) * (plasma volume in L) / (1 - ((f ratio) * (venous hematocrit)))

 

The plasma volume can be measured after intravenous infusion of 125I-labelled albumin.

 

total blood volume in liters =

= (plasma volume) + (red cell volume in liters)

 

To calculate the red cell mass (RCM) the density of erythrocytes is multiplied by the red blood cell volume.

 

density of whole blood: 1.055

density of plasma: 1.027

demsity of erythrocytes 1.096

 

On page 27 the authors reference an f value of 0.864. If this is multiplied by the density of whole blood (1.055) then the value of 0.911 is returned, which is the mean value for f.

 


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