Esophagitis, Gastritis and/or Duodenitis in a Patient with Ulcerative Colitis or Crohn's Disease

 

Inflammatory bowel disease involving the upper GI tract may cause:

(1) focal or diffuse gastritis

(2) focal or diffuse duodenitis

(3) focal or diffuse esophagitis

 

The inflammatory cell infiltrates may consist of:

(1) plasmacytosis in ulcerative colitis (differential diagnosis gastric syphilis)

(2) noncaseating granulomas in Crohn's disease

(3) mucosal ulcerations (differential diagnosis peptic ulcer disease and other conditions)

(4) villous atrophy in the duodenum (differential diagnosis celiac disease)

(5) cryptitis

 

Other forms of gastritis or duodenitis may occur concurrently - Helicobacter gastritis, chemical gastropathy, celiac disease, etc. Persistence of inflammation following treatment of these conditions supports the diagnosis of IBD-related inflammation.