Hibbs et al listed errors that have been reported during the administration of oral live rotavirus vaccine. These can help target steps to reduce their occurrence. The authorus are from the Centers for Disease Control and Prevention.


Vaccine: oral live rotavirus - RotaTeq (Merck & Co) and Rotarix (GlaxoSmithKline)



not reading the package insert

Carefully read the package insert.

misinterpreting the instructions in the package insert

Test understanding after reading the package insert.

injecting the vaccine rather than giving orally

An oral dose needs to be given. Monitor the injection site for local reaction.

inadequate training, especially in giving an oral vaccine

Provide adequate training.

eye splashes during administration

Wear eye protection.

infant spits out, regurgitates or vomits during or after administration

Administer carefully and gently inside the cheek. If spitting, etc occurs then a replacement dose is not indicated.

failure to follow age and dosing instructions

Follow administration guidelines.



• Rotarix is delivered in a syringe and may be mistaken as a parenteral vaccine.


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