A male with sickle cell anemia is at risk of erectile dysfunction (ED).
Clinical features:
(1) presence of homozygous sickle cell disease, hemoglobin SC or related sickling disease
(2) history of recurrent ischemic priapism, especially when prolonged
(3) presence of other risk factors for erectile dysfunction
(4) low blood hemoglobin F
(5) thrombocytosis
The condition may affect young adults less than 30 years of age.
Erectile dysfunction can affect even patients with very minor priapism.
