Theophylline and other methylxanthines relax smooth muscle and are helpful in bronchial asthma and bronchospasm. The dose is relative to theophylline base.
Reference drug: theophylline anhydrous
|
Drug |
Theophylline Fraction |
Dose Equivalent to 1 mg Theophylline Anhydrous |
|
aminophylline anhydrous |
0.86 |
1.16 |
|
aminophylline dihydrate |
0.79 |
1.27 |
|
oxtriphylline |
0.64 |
1.56 |
|
theophylline monohydrate |
0.91 |
1.1 |
|
theophylline sodium glycinate |
0.49 |
2.04 |
|
theophylline calcium salicylate |
0.48 |
2.08 |
where:
• Aminophylline = theophylline compounded with ethylenediamine
|
Drug |
Molecular Weight |
|
aminophylline anhydrous |
420.43 |
|
aminophylline dihydrate |
|
|
oxtriphylline |
|
|
theophylline anhydrous |
180.17 |
|
theophylline monohydrate |
|
|
theophylline sodium glycinate |
|
|
theophylline calcium salicylate |
|
Specialty: Pharmacology, clinical
ICD-10: ,
