Patient selection: adult Caucasians from 45 to 71 years of age, current nonsmoker, no history of lung disease
Parameters:
(1) height in meters
(2) age in years
(3) weight in kilograms
(4) smoking history (0 never smoker, 1 ex-smoker)
carbon monoxide single breath diffusing capacity in mmol/min/kPa for male =
= (1.109 * ((height)^3)) - (0.000402 * ((age)^2)) - (0.035 * (age) * (points for smoking history)) + (1.805 * (points for smoking history)) + A
carbon monoxide single breath diffusing capacity in mmol/min/kPa for female =
= (-3.901 * ((height)^3)) + (51.9 * (height)) + (0.375* (age)) + (0.012 * (weight)) - (0.273 * (age) * (height)) - B
alveolar volume in liters for male =
= (10.155 * (height)) - (0.013 * (weight)) - (0.0000943 * ((age)^2)) - C
alveolar volume in liters for female =
= (7.206 * (height)) - (0.0041 * (weight)) - (0.0073 * (age) * (height)) - D
|
|
A
|
B
|
C
|
D
|
|
mean
|
4.696
|
57.703
|
9.628
|
5.77
|
|
5th percentile
|
2.651
|
59.207
|
10.755
|
6.684
|
|
95th percentile
|
6.741
|
56.2
|
8.501
|
4.856
|
Kco =
= (single breath diffusing capacity) / (alveolar volume)
