Equations of Thenappan et al for Predicting Survival for a Patient with Pulmonary Arterial Hypertension (PAH)

Patient selection: pulmonary arterial hypertension

Outcome: survival at 1, 2 or 3 years

Parameters:

(1) mean pulmonary artery pressure (PAP) in mm Hg

(2) mean right atrial pressure (RAP) in mm Hg

(3) cardiac index (CI) in liters per minute per square meter

(4) coefficient for response to calcium channel blocking (CCB)drugs

X =

= (0.0402 * (mean RAP)) - (0.0148 * (mean PAP)) - (0.361 * (CI)) - (coefficient)

A =

= EXP(X)

probability for surviving N years =

= EXP((-1) * A * N)

where:

• N is 1, 2 or 3 years.