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Equations of Salazar and Corcoran for Predicting Creatinine Clearance in Obese Patients

Description

Salazar and Corcoran developed gender-specific equations for predicting creatinine clearance in obese patients based on serum creatinine and fat free body mass. These equations more accurately predict creatinine clearance than standard equations and can be used to adjust medications for reduced renal function. The authors are from State University of New York in Buffalo and the University of New Mexico in Albuquerque.


 

Patient selection: age not specified but assumed adult; obesity was defined as body mass index > 29.9 kg per square meter

 

Parameters:

(1) serum creatinine in mg/dL

(2) body weight in kilograms

(3) body height in meters

(4) gender

(5) age in years

 

creatinine clearance in mL per minute for a male =

= (137 - (age in years)) * ((0.285 * (body weight in kilograms)) + (12.1 * ((height in meters)^2))) / (51 * (creatinine in mg/dL))

 

creatinine clearance in mL per minute for a female =

= (146 - (age in years)) * ((0.287 * (body weight in kilograms)) + (9.74 * ((height in meters)^2))) / (60 * (creatinine in mg/dL))

 

NOTE: The value for creatinine clearance is not adjusted to body surface area.

 


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