Roach reported 3 equations for predicting the extent of prostate cancer based on serum PSA concentration and the Gleason score. The author is from the University of California in San Francisco.
Parameters:
(1) serum PSA in ng/mL
(2) Gleason score (from 2 to 10)
probability of positive lymph nodes =
= (0.667 * (PSA)) + (10 * ((Gleason score) - 6))
probability of positive seminal vesicles =
= (PSA) + (10 * ((Gleason score) - 6))
probability of positive capsular penetration =
= (1.5 * (PSA)) + (10 * ((Gleason score) - 3))
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