 ### Description

Ong et al evaluated pulmonary function tests in malnourished children from West Bengal, India. They identified equations that can be used to estimate target values based on sitting height and weight. The authors are from the University of Dundee.

Patient selection: malnourished children from 3 to 17 years (page 18)

Parameters:

(1) sitting height in cm

(2) body weight in kilograms

Predicted pulmonary function tests:

(1) FEV1 (forced expiratory volume in 1 second) in liters

(2) FVC (forced vital capacity) in liters

(3) PEFR (peak expiratory flow rate) in liters per second

observed pulmonary function test as percent of predicted =

= (observed value) / (predicted) * 100%

For Boys

predicted FEV1 in liters =

= EXP(X)

X =

= (1.080 * (LN(sitting height))) + (0.657 * (LN(weight))) - 6.261

predicted FVC in liters =

= EXP(Y)

Y =

= (LN(sitting height)) + (0.669 * (LN(weight))) - 5.918

predicted PEFR in liters per second =

= EXP(Z)

Z =

= (0.781 * (LN(sitting height))) + (0.614 * (LN(weight))) + 0.378

For Girls

predicted FEV1 in liters =

= EXP(X)

X =

= (1.268 * (LN(sitting height))) + (0.518 * (LN(weight))) - 6.667

predicted FVC in liters =

= EXP(Y)

Y =

= (1.233 * (LN(sitting height))) + (0.527 * (LN(weight))) - 6.529

predicted PEFR in liters per second =

= EXP(Z)

Z =

= (1.545 * (LN(sitting height))) + (0.338 * (LN(weight))) - 2.093

NOTE: While working on the spreadsheet it became apparent that the predicted PEFR by these equations are significantly higher than expected and what seems reasonable. Using -7.093 for girls gives a more reasonable value, suggesting a typographical error. Alternatively the PEFR value does not need to be made EXP.

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