Vergunst et al reported an equation for predicting the 1-year glomerular filtration rate for a patient with ANCA-associated glomerulonephritis. Renal function at the time of biopsy is the best predictor for renal function in 1 year. The authors are from Leiden University Medical Center in The Netherlands.
Patient selection: ANCA-associated glomerulonephritis (Wegener's granulomatosis, microscopic polyangiitis, idiopathic rapidly progressive GN without immune deposits)
Parameters:
(1) GFR at baseline (using Cockcroft equation)
(2) glomerular features on histology
(3) fibrinoid necrosis
(4) age in years
Parameter
Finding
Points
GFR at baseline
0.65 * (GFR)
fibrinoid necrosis
absent
0
present
7.72
glomerular histology
normal
10.52
other
0
age
-0.42 * (age)
predicted GFR in 1 year in mL per min =
= SUM(points for all of the parameters) + 36.96
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