An eosinophilic folliculitis may develop in an HIV-1 infected patient. This may be related to Ofuji's disease, an eosinophilic pustular folliculitis described in the Japanese (? associated with HTLV-I infection?).
Patient at risk:
(1) advanced HIV disease (high plasma RNA and/or low CD4 lymphocyte count)
(2) not receiving HAART
Clinical features:
(1) marked pruritus
(2) erythematous papules and/or urticaria
(3) centrally located (head, neck, thorax, abdomen, proximal extremities)
Laboratory findings:
(1) absolute or relative eosinophilia
(2) elevated serum IgE
Biopsy findings:
(1) eosinophilic infiltrate in and about hair follicules with CD8 positive T cells
(2) lytic degeneration of sebaceous glands
Differential diagnosis - Diagnosis requires exclusion of:
(1) bacterial folliculitis
(2) fungal folliculitis
(3) drug reaction
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Purpose: To evaluate an HIV-infected patient for eosinophilic folliculitis.
Specialty: Dermatology
Objective: criteria for diagnosis, complications
ICD-10: B20.9,
