Description

Eosinophilic Esophageal Myositis (EoEM) is one of the eosinophilic esophageal disorders that is distinct from eosinophilic esophagitis.


Clinical features:

(1) chest pain

(2) dysphagia with food impaction

(3) luminal compression on endoscopy

(4) abnormal manometry

(5) jackhammer or nutcracker esophagus

 

Laboratory findings:

(1) elevated serum IgE concentration

 

Biopsies or FNA aspirates show:

(1)  no or few eosinophils in the esophageal mucosa

(2) increased eosinophils in the muscularis propria

 

The diagnosis requires exclusion of other causes of an eosinophilic infiltrate such as parasitic infection.


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