Sarcoidosis can result in enlargement of the parotid and other salivary glands.


General clinical findings in patients with sarcoidosis:

(1) respiratory symptoms (dyspnea, coughing and chest pain) with pulmonary infiltrate and hilar lymphadenopathy

(2) elevated serum angiotensin converting enzyme (ACE)

(3) noncaseating granulomas in biopsies of lymph nodes or organs


Changes in salivary glands:

(1) There is unilateral or bilateral enlargement of the parotid and/or submandibular glands.

(2) The salivary glands are firm on palpation.

(3) The salivary glands may be slightly painful.

(4) Saliva production is reduced.

(5) The salivary glands do not change in size while eating.

(6) The parotid ducts appear normal on sialogram with a reduced number of ducts.


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