A slow-growing endobronchial carcinoid tumor may mimic asthma if it causes partial bronchial obstruction.
Clinical features of a carcinoid tumor with partial airway obstruction:
(1) wheezing, which is typically unilateral
(2) cough
(3) shortness of breath
(4) chest pain or discomfort
Reasons to suspect the diagnosis:
(1) failure to respond to appropriate asthma therapy
(2) consequences of progressive airway obstruction (see below)
(3) secretion of a biologically active compound
(4) lesion seen on imaging study or endoscopy
(5) hemoptysis
(6) onset of symptoms as a middle-aged or older adult
(7) spirometric evidence of obstruction with a biphasic flow-volume loop
With more obstruction the patient may develop:
(1) recurrent pneumonia
(2) atelectasis
(3) bronchiectasis
(4) lung abscess
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Specialty: Hematology Oncology, Surgery, general, Pulmonology