Patient selection: preterm infant
Parameters:
(1) gestational age in weeks
(2) birth weight in grams
(3) neonatal respiratory distress syndrome (RDS)
(4) mechanical ventilation (MV)
(5) peak inspiratory pressure in cm H2O
(6) FIO2 (from 0.21 to 1.00)
(7) pulmonary interstitial emphysems (PIE)
(8) patent ductus arteriosus (PDA)
(9) intracranial hemorrhage (ICH) grade (intraventricular hemorrhage)
(10) sepsis
points for peak inspiratory pressure in cm H2O =
= 0.1 * (cm H2O)
points for FIO2 =
= 10 * ((FIO2) – 0.21)
|
Parameter
|
Finding
|
Points
|
|
gestational age in weeks
|
< 30 weeks
|
1
|
|
|
>= 30 weeks
|
0.5
|
|
birth weight in grams
|
< 1000 grams
|
1
|
|
|
>= 1000
|
0.5
|
|
neonatal RDS
|
hyaline membrande disease (HMD)
|
1
|
|
|
other
|
0.5
|
|
|
none
|
0
|
|
mechanical ventilation
|
no
|
0
|
|
|
yes
|
1
|
|
pulmonary interstitial emphysema
|
no
|
0
|
|
|
yes
|
1
|
|
patent ductus arteriosus
|
no
|
0
|
|
|
yes
|
0.5
|
|
intracranial hemorrhage
|
none or Grade <= 2
|
0
|
|
|
Grade 3 or 4
|
0.5
|
|
sepsis
|
no
|
0
|
|
|
yes
|
0.5
|
where:
• A category for none for neonatal RDS included based on Table 1 and minimum score.
total score =
= SUM(points for all 10 parameters)
Interpretation:
• minimum score: around 1
• maximum score: around 12.4
• A score >= 4 indicates a neonate who will develop chronic lung disease (CLD).
Performance:
• The sensitivity was 93% and specificity 97%.
• The predictive value was 97%.
• The area under the ROC curve was 0.964.
