A person with diabetes mellitus may be a candidate for pancreas transplant if certain criteria are present.


Type of Transplant

Creatinine Clearance

pancreas transplant alone (PTA)

usually > 60 mL/min; may be given in 40-60 mL/min range

sequential pancreas after kidney transplant (PAKT)

usually > 40 mL/min

pancreas and kidney transplant, simultaneous (SKPT)

usually < 30 mL/min


Diabetes status criteria

(1) presence of insulin-dependent diabetes mellitus

(2) presence of 2 or more diabetic complications (proliferative retinopathy, diabetic nephropathy, peripheral or autonomic neuropathy, microangiopathy, accelerated atherosclerosis, difficult glucose control with frequent ketoacidosis and/or hypoglycemia)


General health status criteria:

(1) sufficient cardiopulmonary function

(2) able to undergo surgery

(3) able to withstand immunosuppression

(4) absence of any organ failures other than renal failure


Patient status criteria:

(1) emotionally and psychologically suitable

(2) sufficient social support and economic resources

(3) compliant with long term drug regimens


To read more or access our algorithms and calculators, please log in or register.