Elevated AST ALT Levels | Medical Algorithm

Are you evaluating a patient who has experienced hepatocellular injury?

Yes

Initial serum serum AST level

Upper limit of reference range for AST

Initial serum serum ALT level

Upper limit of reference range for ALT

Number of hours between initial and final measurement of AST and ALT

hours

Final serum serum AST level

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Data complete?

Evaluation appropriate?

Expected serum AST level at time assuming transient injury

Expected time for the AST to normalize assuming transient hepatic injury

Final AST concentration as multiple of the upper limit of normal

Expected serum ALT level at time assuming transient injury

Expected time for the ALT to normalize assuming transient hepatic injury

Final ALT concentration as multiple of the upper limit of normal

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Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Specialty

Objective

ICD-10

Half-Lives of AST & ALT Relative to Hepatocellular Injury

Purpose: To evaluate a patient who has had a hepatocellular injury by monitoring the decline in serum transaminases over time with first order kinetics.

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Specialty

Objective

ICD-10