The Elderly International Prognostic Index (E-IPI) is used to evaluate older adults with diffuse large B-cell lymphoma (DLBCL).
Patient selection: diffuse large B-cell lymphoma with age > 60 years.
Parameters:
(1) age of the patient in years
(2) serum LDH in U/L relative to the upper limit of the normal reference range (ULN)
(3) ECOG performance status
(4) Ann Arbor stage
(5) extranodal sites
Parameter
Finding
Points
age of the patient
< 70 years
0
>= 70 yeaers
1
serum LDH
<= ULN
> ULN
ECOG performance
0 or 1
2 to 4
Ann Arbor stage
I or II
III or IV
extranodal sites
>= 1
where:
• Risk factors differ from the IPI with age and extranodal sites.
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
Elderly IPI Score
Risk Group
3-Year Overall Survival
low
86%
2
low-intermediate
74%
3
high-intermediate
58%
4 or 5
high
36%
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Specialty: Hematology Oncology
