Eggshell calcification of the lymph nodes may be seen on imaging studies of the chest.


Criteria for the diagnosis of eggshell calcification:

(1) peripheral shell-like calcification <= 2 mm in thickness affecting >= 2 lymph nodes

(2) >= 1 lymph node >= 1 cm in diameter

(3) complete ring-like shadow in >= 1 lymph node (may be broken in the other nodes)

Additional calcifications may be present in the center of the lymph node.


Conditions associated with eggshell calcification of lymph nodes:

(1) coal workers pneumoconiosis (common)

(2) other forms of silicosis (common)

(3) deep fungal infection (histoplasmosis, blastomycosis)

(4) sarcoidosis

(5) post-radiation change in Hodgkin’s disease

(6) amyloidosis


Differential diagnosis:

(1) cross-section of bronchus

(2) atherosclerosis of aorta

(3) thymic cyst

(4) parathyroid or thyroid tumor

(5) pulmonary artery in pulmonary hypertension


To read more or access our algorithms and calculators, please log in or register.