Adverse effects:
(1) allergic reactions (see below)
(2) cardiovascular effects (see below)
(3) gastrointestinal effects (see below)
(4) neurologic effects (see below)
(5) elevations in serum transaminases and CK
(6) pain at the site of infusion if infused peripherally (due to high osmolality)
Allergic reactions may include:
(1) anaphylactoid reaction
(2) flushing
(3) bronchospasm
(4) pulmonary edema
Cardiovascular effects may include:
(1) bradycardia
(2) heart block
(3) hypotension or shock
(4) cardiac arrest
Gastrointestinal side effects may include:
(1) unpleasant smell or taste
(2) nausea and vomiting
(3) diarrhea
Neurologic effects may include:
(1) headache
(2) seizures
The differential diagnosis includes:
(1) bacterial contamination of the product
(2) hemolytic reaction
(3) allergic reaction to another drug
(4) progression of underlying disease