Description

The effective half-life for a radionuclide within the body is the period of time needed for the compound to be decreased by 50%. This occurs due to the combined effect of the biological half-life and the physical half-life for the compound.


Definitions:

(1) The biological half-life is the time required for half of the material to be eliminated from body through excretion in urine, stool, sweat or other routes.

(2) The physical half-life is the time required for the compound to loss half of its activity through radioactive decay.

 

effective half-life =

= ((biological half-life) * (physical half-life)) / ((biological half-life) + (physical half-life))


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