Description

Moller et al developed an echographic scoring scheme for evaluating severity of heart disease in patients with the carcinoid syndrome. This can help monitor patients over time and to detect cardiac disease progression. The authors are from the Mayo Clinic.


Parameters:

(1) tricuspid valve anatomy

(2) tricuspid valve regurgitation

(3) pulmonic valve anatomy

(4) pulmonic valve regurgitation

(5) right venticular size

(6) right ventricular function

(7) systolic flow reversal in hepatic veins

(8) diastolic forward flow in the pulmonary artery

 

Parameter

Finding

Points

tricuspid valve anatomy

normal

0

 

thickened with reduced mobility

1

 

thickened with severe immobility

2

 

thickened and fixed

3

tricuspid valve regurgitation

none or minimal

0

 

mild

1

 

moderate

2

 

severe

3

pulmonic valve anatomy

normal

0

 

thickened with reduced mobility

1

 

thickened with severe immobility

2

 

thickened and fixed

3

pulmonic valve regurgitation

none or minimal

0

 

mild

1

 

moderate

2

 

severe

3

right ventricular size

normal

0

 

mildly enlarged

1

 

moderately enlarged

2

 

severely enlarged

3

right ventricular function

normal

0

 

mildly impaired

1

 

moderately impaired

2

 

severely impaired

3

systolic flow reversal in hepatic veins

absent

0

 

present

1

diastolic forward flow in the pulmonary artery

absent

0

 

present

1

 

total score =

= SUM(points for all 8 parameters)

 

change from baseline =

= ((current score) – (baseline score)) / (baseline score)

 

Interpretation:

• minimum score: 0

• maximum score: 20

• An increase in the score by >= 25% (> 5 points if baseline score 0) from baseline indicates clinically important progression of the heart disease.

 

Risk factors for progression:

(1) increasing 5-HIAA excretion in the level

(2) history of previous chemotherapy


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