Description

Prediction of mortality following myocardial infarction can be made based on clinical data obtained shortly after the infarct, providing an estimate before hospital discharge. This was developed at the University of Copenhagen in Denmark.


 

Parameters:

(1) age of patient in years

(2) left ventricular ejection fraction by echocardiography performed up to 72 hours after the myocardial infarction

(3) the maximum Killip class during the admission, corresponding to the worst cardiogenic state

 

Killip class

Clinical Findings

Clinical Group

Killip Class

no clinical signs of cardiac decompensation

no heart failure

I

heart failure, with rales, S3 gallop and venous hypertension

heart failure

II

frank pulmonary edema

severe heart failure

III

hypotension (systolic blood pressure <= 90 mm Hg), cyanosis, oliguria, diaphoresis, pulmonary edema

cardiogenic shock

IV

 

Mortality Calculation for 2 and 12 Months

 

mortality at 2 months =

= 1 - EXP((-1) * (X))

 

X =

= (0.051 * EXP((Y)))

 

Y =

= (0.044 * ((age) - 60)) - (0.117 * ((left ventricular ejection fraction) - 40))

 

where:

• The ejection fraction is the percent from 0 to 100.

 

mortality at 1 year =

= 1 - EXP((-1) * (A))

 

A =

= (0.101 * EXP((B)))

 

B =

= (0.408 * ((maximum Killip class) - 1)) - (0.061 * ((left ventricular ejection fraction) - 40))

 


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