Description

Hashimoto et al reported findings associated with lethal tachyarrhythmias in a patient with chronic kidney disease (CKD). These can help to identify a patient who may benefit from more aggressive management. The authors are from multiple institutions in Japan.


Patient selection: chronic kidney disease

Patient assessment: 24-hour Holter monitoring

 

Outcomes: tachyarrhythmias and/or sudden cardiac death

 

Predictors of lethal ventricular tachyarrhythmias:

(1) worst values of ambulatory-based late potentials

(2) nonsustained ventricular tachycardia (NSVT)

 

Worst late potentials:

(1) measurements when the RMS40 was the smallest over 24 hours

(2) considered positive with >= 2 out of 3 readings: fQRS > 135 ms, RMS40 < 15 µV, LAS40 > 30 ms

 

Number of Predictors

Event Free at 20 Months

0

99%

1

90%

2

23%

from Figure 2


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