Chen et al developed a protocol for evaluating the response of a schizophrenic patient to therapy with an atypical antipsychotic agent. This can help to decide if therapy should be continued or changed. The authors are from National Sun Yat-sen University in Kaohsiung, Taiwan.
Patient selection: schizophrenia starting therapy
Therapy: optimal dosage of olanzapine, risperidone and palipeeridone (atypical antipsychotics)
Goal: to predict treatment response at 12 weeks based on response after 2 and 4 weeks of therapy
Parameters:
(1) PANSS (Positive and Negative Syndrome Scale), which ranges from 30 to 210
(2) treatment response after 2 and 4 weeks of therapy
