Backstrom et al reported predictors of mortality in patients newly diagnosed with Parkinson's disease. A patient with Parkinson's disease is at risk for a shorter survival. The authors are from Umea University, University of Gothenburg, Sahlgrenska University Hospital and University College London.

Patient selection: new-onset Parkinson's disease


Predictors of mortality:

(1) cognitive impairment (dementia worse than mild cognitive impairment)

(2) freezing of gait

(3) hyposmia

(4) reduced dopamine transporter activity in the caudate

(5) CSF leukocytosis, even if subtle

(6) postural imbalance and gait disorder (PIGD) or intermediate (not tremor predominant)


A patient with Parkinson's disease but is free of predictors may have a nearly normal life expectancy.

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