Pamecha et al reported the early graft loss risk (e-GLR) score for predicting early graft loss for an adult receiving a live donor liver transplant. The authors are from Institute of Liver & Biliary Sciences in New Delhi.
Patient selection: live-donor liver transplant
Outcome: graft loss within 90 days
Parameters:
(1) donor age
(2) estimated graft weight in grams
(3) actual graft weight in grams
(4) MELD score
Parameter
Finding
Points
donor age
0.052 * (age)
estimated graft weight
< 640 grams
1.681
>= 640 grams
0
MELD score
0.145 * (MELD)
e-GLR score using estimated graft weight =
= (10 * SUM(points for the 3 parameters)) - 8.608
Parameter
Finding
Points
donor age
0.054 * (age)
actual graft weight
< 610 grams
1.851
>= 610 grams
0
MELD score
0.128 * (MELD)
e-GLR score using actual graft weight =
= (10 * SUM(points for all 3 parameters)) - 8.128
e-GLR score
90-Day Risk of Graft Loss
<= 54
< 10%
55 to 60
11 to 15%
61 to 66
16 to 24%
67 to 72
25 to 33%
73 to 78
34 to 45%
> 78
> 45%
Performance:
• The area under the ROC curve for the estimated weight was 0.81 in the derivation and 0.86 in the validation cohorts.
• The area under the ROC curve for the actual weight was 0.86 in the derivation and 0.84 in the validation cohorts.
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