A number of drugs may be associated with rhinitis.


Synonym: rhinitis medicamentosa (some people restrict this term to rebound rhinitis)


Criteria for the diagnoiss of drug-induced rhinitis:

(1) onset of or worsening of rhinitis after starting a drug

(2) discontinuation of the drug results in improvement of rhinitis symptoms

(3) no other explanation identified


Drugs associated with rhinitis:

(1) antihypertensive drugs

(2) phosphodiesterase type 5 inhibitors (sildenafil, other)

(3) estrogen or oral contraceptives

(4) analgesics (aspirin, NSAIDS)

(5) psychotropic drugs (thioridazine, risperidone, chlorpromazine, other)

(6) gabapentin

(7) cocaine


Some drugs may cause rhinitis due to impairment of host defenses and not due to a direct drug effect:

(1) corticosteroids

(2) chemotherapy

(3) immunosuppression


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