Microscopic colitis may be drug-induced.
Features:
(1) diarrhea
(2) biopsy evidence of microscopic colitis (collagenous or lymphocytic)
(3) onset after starting an implicated drug
(4) resolution after discontinuing the implicated drug
(5) exclusion of other causes
(6) variable presence of psoriasis or other immune disorder, which also clears or improves after drug discontinuation
Drugs with an intermediate or high likelihood of causing microscopic colitis include:
(1) acarbose
(2) aspirin
(3) carbamazepine
(4) flutamide
(5) lansoprazole
(6) lisinopril
(7) NSAIDs
(8) oxetorone
(9) paroxetine
(10) ranitidine
(11) sertaline
(12) simvastatin
(13) tardyferon
(14) ticlopidine
(15) vinburine
