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Drug-Induced Liver Injury Network (DILIN) Grading Criteria

Purpose: To determine the severity of drug-induced liver injury (DILI) using the criteria of the DILIN.

Evaluation

Are you evaluating a patient with drug-induced liver injury?

Does the patient have?

• fatigue?

• nausea?

• vomiting?

• right upper quadrant pain?

• itching?

• skin rash?

• jaundice?

• weakness?

• anorexia?

• weight loss?

Serum ALT

IU/L

Upper limit of normal for serum ALT

IU/L

Serum alkaline phosphtase

IU/L

Upper limit of normal for serum alkaline phosphatase

IU/L

Serum total bilirubin

INR

Was the patient hospitalized or was a hospital stay prolonged because of DILI?

Does the patient have evidence of hepatic encephalopathy?

Has the patient developed failure of an organ other than the liver because of DILI?

Has the patient required a liver transplant because of the DILI?

Did the patient die because of DILI?

Results

Please fill out required fields.

Specialty

Objective

ICD-10