Therapy with a number of drugs may be linked to development of dental caries.
Classes of drugs that may be associated with dental caries:
(1) antidepressants
(2) antiepileptics
(3) antipsychotics
(4) atropinic drugs
(5) beta-2 adrenoreceptor agonist drugs
(6) bisphosphonates
(7) corticosteroids
(8) immunomodulating drugs
(9) opioids
Pathogenesis of the dental caries:
(1) changes in salivary flow and/or composition (reduced flow, low pH), particularly drugs with antimuscarinic activity
(2) changes in bone metabolism (with demineralization)
(3) hyperglycemia
(4) immunosuppression
(5) unspecified
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Specialty: Otolaryngology
