Exposure to a number of drugs or chemicals can result in cataract development.
Some exposures require high doses and/or prolonged therapy.
Drug or Chemical
Type of Cataract
allopurinol (gout medications)
posterior subcapsular (white flaky)
stellate opacities; anterior polar; brownish-yellow granules in anterior capsule
anterior capsular and subcapsular deposits, sunflower-type
anterior capsular deposits
anterior and/or posterior subcapsular
Quetiapine fumarate (antipsychotic)
• Desferoxamine-related cataracts need to be distinguished from cataracts caused by the metal being chelated.
(1) cataracts associated with drug-induced renal failure
(2) cataracts associated with drug-induced glaucoma
(3) cataracts associated with gout
(4) cataracts due to other causes
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